BDBM206048 (S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A49

SMILES COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(C)(C)F

InChI Key InChIKey=AEBNLOFIJHRQAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206048   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206048BDBM206048((S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methyl...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206048BDBM206048((S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent