BDBM206058 5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((R)-2,6- dioxopiperidin-3-yl)picolinamide formate::US20260007681, Compound A57

SMILES COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)N[C@@H]1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F

InChI Key InChIKey=OYMOSSFRFJBEGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206058   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206058BDBM206058(5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-meth...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent