BDBM206764 (R)-3-((S)-7-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-1-oxo-1,3,5,5a,6,7,8,9- octahydro-2H- pyrazino[1'2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A59

SMILES C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@@H](CN8CCN7c6ccc5C(=O)N([C@@H]4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F

InChI Key InChIKey=PLUMUKVJAXKYNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206764   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206764BDBM206764((R)-3-((S)-7-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroe...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206764BDBM206764((R)-3-((S)-7-(((S)-8-(5-((1S,3S)-2-(2,2- difluoroe...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent