BDBM206768 (R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)-N-((S)-2,6-dioxopiperidin-3- yl)-1,2,3,4,4a,5-hexahydropyrazino[1,2- d]pyrido[2,3-b][1,4]oxazine-8- carboxamide::US20260007681, Compound A63

SMILES C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N3CCC8(CC3)C[C@@H](CN7CCN6c5ccc(C(=O)N[C@H]4CCC(=O)NC4=O)nc5OC[C@H]6C7)CO8)nc9)N%10CC(F)F

InChI Key InChIKey=YNHWAMPKCMEBHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206768   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206768BDBM206768((R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206768BDBM206768((R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent