BDBM209009 US9233167, 6-O-mPEG8-Nalbuphine

SMILES COCCOCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC1CCC1)c45

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 209009   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM209009(US9233167, 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  79.5nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2017
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM209009(US9233167, 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  168nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2017
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM209009(US9233167, 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  282nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2017
Entry Details
US Patent