BDBM20917 Isoxazole, 40j::N-ethyl-5-{5-[2-(3-fluorophenyl)ethyl]-2,4-dihydroxyphenyl}-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide

SMILES CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(CCc2cccc(F)c2)c(O)cc1O

InChI Key InChIKey=ZEVCEUSBFMYXLZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20917   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM20917(N-ethyl-5-{5-[2-(3-fluorophenyl)ethyl]-2,4-dihydro...)
Affinity DataIC50: 26nM EC50:  58nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed