BDBM209466 US10328074, Example III-7::US11077107, Example III-7::US9266891, III-7
SMILES CNc1nc(cn2c(C)nnc12)-c1nc2ccccc2n1Cc1ccccc1
InChI Key InChIKey=GPMKACUDCQFCCA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 209466
TargetBromodomain-containing protein 4 [44-168]/Histone H4(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 22nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 22nMAssay Description:This assay is used to determine whether the compounds inhibit the interaction between the first (BRD4-BD1) or the second (BRD4-BD2) bromodomain of BR...More data for this Ligand-Target Pair