BDBM209537 US9271969, 25

SMILES O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)NCc5ccc(Oc6ccc(F)cc6)cc5)cn4c3)cc2)CC1

InChI Key InChIKey=KCRCHBNFVZPCKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209537   

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209537BDBM209537(US9271969, 25)
Affinity DataIC50: 5.30nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209537BDBM209537(US9271969, 25)
Affinity DataIC50: 16.8nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent