BDBM209566 US9271969, 54

SMILES O=C(O)CC1CCC(c2ccc(-c3cn4cc(C(=O)NC5(c6cc(F)ccc6F)CC5)nc4s3)cc2)CC1

InChI Key InChIKey=TXFWIUPMSPUEGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209566   

TargetDiacylglycerol O-acyltransferase 1(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209566BDBM209566(US9271969, 54)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 209566BDBM209566(US9271969, 54)
Affinity DataIC50: 25nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent