BDBM210789 US10463663, Example 24::US11129828, Example 24::US9290456, 24::US9931340, Example 24

SMILES Cc1cc(CCc2cc(O)c(=O)[nH]n2)ccc1F

InChI Key InChIKey=AJSWASRGBNDGAM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 210789   

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210789(US10463663, Example 24 | US11129828, Example 24 | ...)
Affinity DataIC50:  6nMpH: 7.4 T: 25°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210789(US10463663, Example 24 | US11129828, Example 24 | ...)
Affinity DataIC50:  6nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210789(US10463663, Example 24 | US11129828, Example 24 | ...)
Affinity DataIC50:  6nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210789(US10463663, Example 24 | US11129828, Example 24 | ...)
Affinity DataIC50:  6nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent