BDBM210809 US10463663, Example 47::US11129828, Example 47::US9290456, 47::US9931340, Example 47

SMILES Cc1ccc(Cc2cc(O)c(=O)[nH]n2)cc1

InChI Key InChIKey=NSNMVUVQLQLHEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 210809   

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210809(US9290456, 47 | US9931340, Example 47 | US10463663...)
Affinity DataIC50: 26nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210809(US9290456, 47 | US9931340, Example 47 | US10463663...)
Affinity DataIC50: 26nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2020
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210809(US9290456, 47 | US9931340, Example 47 | US10463663...)
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM210809(US9290456, 47 | US9931340, Example 47 | US10463663...)
Affinity DataIC50: 26nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent