BDBM211305 US9247759, 10-53::US9247759, 10-88

SMILES Cc1noc(C)c1Cn1cc(cn1)N1C(=O)CN(Cc2ccccc2)C1=O

InChI Key InChIKey=AYGGIMJXTALZIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 211305   

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM211305(US9247759, 10-88 | US9247759, 10-53)
Affinity DataIC50: 90nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
US Patent

TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM211305(US9247759, 10-88 | US9247759, 10-53)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTaste receptor type 2 member 8(Human)
Senomyx

US Patent
LigandPNGBDBM211305(US9247759, 10-88 | US9247759, 10-53)
Affinity DataIC50: 710nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
US Patent