BDBM211501 US9290457, Example 1.43

SMILES CN1CCC(C1)NC(=O)c1cc(ccc1C1N(C)C(=O)N(C(C)=C1C(C)=O)c1cccc(c1)C(F)(F)F)C#N

InChI Key InChIKey=BIWIVXWIEPGHOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 211501   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM211501(US9290457, Example 1.43)
Affinity DataIC50: <1nMpH: 7.5 T: 25°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent