BDBM211853 US9290459, 41.16::US9670166, 41.16
SMILES FC(F)(F)c1cccc(c1)N1C2=C(C(N(C(=O)NC3CCOCC3)C1=O)c1ccc(cc1)C#N)C(=O)CC2
InChI Key InChIKey=KJULILWHIITOOS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 211853
Affinity DataEC50: 2nMpH: 7.5Assay Description:Various concentrations of the neutrophil elastase inhibitor are incubated with plasma. Subsequently, the enzyme activity is measured using the fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.5 T: 25°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.5 T: 25°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair