BDBM211875 US9290459, 42.6::US9670166, 42.6
SMILES O[C@@H]1COC[C@@H]1NC(=O)N1C(C2=C(CCC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N
InChI Key InChIKey=AAKKMOYZQNTGLG-ZBUVYOTDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 211875
Affinity DataEC50: 1nMpH: 7.5Assay Description:Various concentrations of the neutrophil elastase inhibitor are incubated with plasma. Subsequently, the enzyme activity is measured using the fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.5 T: 25°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.5 T: 25°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair