BDBM212293 US9290507, I-13

SMILES Cc1ccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)cc1-n1cc(-c2cncc(N3CCOCC3)c2)nn1

InChI Key InChIKey=VXQIFGOGSQNXMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212293   

TargetSerine/threonine-protein kinase B-raf(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 212293BDBM212293(US9290507, I-13)
Affinity DataIC50: 12nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase 25(Human)
University of Montreal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 212293BDBM212293(US9290507, I-13)
Affinity DataIC50: 12nMAssay Description:Inhibition of STK25 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed