BDBM212444 US9278093, 4

SMILES Cc1nnc2CCc3cc(cc(F)c3-n12)-c1cncc(F)c1Cl

InChI Key InChIKey=WNDOZKLKOVRGMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212444   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212444(US9278093, 4)
Affinity DataIC50: 21.6nMT: 2°CAssay Description:Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212444(US9278093, 4)
Affinity DataIC50: 9.80E+3nMT: 2°CAssay Description:Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent