BDBM21354 2-{1-[(5-chlorothiophene-2-)sulfonyl]-1H-indol-3-yl}ethan-1-amine::thiophene sulfonyltryptamine, 11m

SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)s1

InChI Key InChIKey=FSQBPWLJULPEEW-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21354   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21354(2-{1-[(5-chlorothiophene-2-)sulfonyl]-1H-indol-3-y...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human 5-HT6 receptor expressed in HeLa cells after 120 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21354(2-{1-[(5-chlorothiophene-2-)sulfonyl]-1H-indol-3-y...)
Affinity DataKi:  6nM ΔG°:  -11.1kcal/mole EC50:  181nMpH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed