BDBM21509 4-[2-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)ethyl]morpholine::Dihydropyrrolopyrazole, 15d
SMILES C(CN1CCOCC1)Oc1ccc2c(ccnc2c1)-c1c2CCCn2nc1-c1ccccn1
InChI Key InChIKey=IHLVSLOZUHKNMQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 21509
Affinity DataKi: 38nMAssay Description:Inhibition of TbetaR-1 (unknown origin) assessed as inhibition constant by ELISA assayMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of TbetaR-2 (unknown origin) assessed as inhibition constant by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of TGFbetaR1 in human primary T-cells assessed as TGFbeta-stimulated PSMAD phosphorylation preincubated for 1 hr followed by TGFbeta addit...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nM EC50: 180nMpH: 7.5 T: 2°CAssay Description:The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of wild type His-tagged TGFbetaR2 (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair