BDBM215738 US9296748, II-25

SMILES CC1=CC(=NN(C1=O)C)c2nc3cnc(cc3n2[C@@H](C)c4ccccc4)C5CCOCC5

InChI Key InChIKey=QNFGQQDKBYVNAS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215738   

TargetBromodomain-containing protein 4 [44-168](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM215738(US9296748, II-25)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM215738(US9296748, II-25)
Affinity DataIC50: 8nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed