BDBM215877 US9302989, 73

SMILES O=C(Nc1ccc(cc1)C(=O)NCc1ccccc1)N1Cc2ccccc2C1

InChI Key InChIKey=FTJMDFVKGPQHIP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215877   

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM215877(US9302989, 73)
Affinity DataKi:  19nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM215877(US9302989, 73)
Affinity DataIC50:  26.7nMpH: 7.5Assay Description:Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...More data for this Ligand-Target Pair
In DepthDetails US Patent