BDBM21634 (2S)-2-[2-(diphenylmethyl)-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanoic acid::Mercaptoacyl amino acid compound, (rac)-8::racemic mixture

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(CS)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=RSRFAHTWPLPZSJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21634   

TargetNeprilysin(Rabbit)
Cnrs

LigandPNGBDBM21634(racemic mixture | (2S)-2-[2-(diphenylmethyl)-3-sul...)
Affinity DataKi:  140nM ΔG°:  -9.72kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
LigandPNGBDBM21634(racemic mixture | (2S)-2-[2-(diphenylmethyl)-3-sul...)
Affinity DataKi:  250nMAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
LigandPNGBDBM21634(racemic mixture | (2S)-2-[2-(diphenylmethyl)-3-sul...)
Affinity DataKi: >1.00E+4nMAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed