BDBM216345 US9302989, 290

SMILES CC(C)CCNC(=O)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1

InChI Key InChIKey=LMYQDAFZILWDHN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 216345   

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM216345(US9302989, 290)
Affinity DataKi:  7.5nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM216345(US9302989, 290)
Affinity DataIC50:  10.4nMpH: 7.5Assay Description:Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent