BDBM217044 US9302989, 336

SMILES O=C(Nc1ccc(cc1)N1CCN(CC1)C(=O)c1ccccc1)N1Cc2ccccc2C1

InChI Key InChIKey=HCQKWBKNBHARJA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 217044   

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM217044(US9302989, 336)
Affinity DataKi:  19nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide phosphoribosyltransferase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM217044(US9302989, 336)
Affinity DataIC50:  25.9nMpH: 7.5Assay Description:Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent