BDBM218343 US9284333, 16ci::US9884860, Example 16ci

SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=DWMYZHDZTBDFJZ-IFXJQAMLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218343   

LigandPNGBDBM218343(US9284333, 16ci | US9884860, Example 16ci)
Affinity DataIC50:  1.00E+4nMT: 25°CAssay Description:The effect of compounds of the formula I on the cloned human cardiac hERG channel was evaluated in an in vitro model using a whole-cell patch-clampin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM218343(US9284333, 16ci | US9884860, Example 16ci)
Affinity DataIC50:  30nMT: 25°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM218343(US9284333, 16ci | US9884860, Example 16ci)
Affinity DataIC50:  30nMT: 25°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent