BDBM22044 (5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]methylidene}-1-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione::(5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]methylidene}-1-prop-2-en-1-ylpyrimidine-2,4,6(1H,3H,5H)-trione::pyrimidine-2,4,6(1H,3H,5H)-trione, 3

SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1ccc(\C=C2\C(=O)NC(=O)N(CC=C)C2=O)o1

InChI Key InChIKey=GSAVRXQYVUXVNR-LCYFTJDESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22044   

TargetProtein kinase YpkA(Yersinia pestis)
The Rockefeller University

LigandPNGBDBM22044((5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]meth...)
Affinity DataIC50:  9.72E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
The Rockefeller University

LigandPNGBDBM22044((5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]meth...)
Affinity DataIC50:  2.05E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
The Rockefeller University

LigandPNGBDBM22044((5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]meth...)
Affinity DataIC50:  5.45E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed