BDBM22201 1,3,4-oxadiazole based compound, 9::1-({4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]phenyl}methyl)azetidine-3-carboxylic acid::1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]benzyl}azetidine-3-carboxylic acid

SMILES CC(C)(C)c1ccc(cc1)-c1nnc(o1)-c1ccc(CN2CC(C2)C(O)=O)cc1

InChI Key InChIKey=CCKXTEGCXIXMQR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22201   

TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM22201(1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 10nMAssay Description:Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

LigandPNGBDBM22201(1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

LigandPNGBDBM22201(1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 100nMAssay Description:Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

LigandPNGBDBM22201(1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

LigandPNGBDBM22201(1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 4.30E+3nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM22201(1-{4-[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed