BDBM222461 (E)-4-[2-(4-Chloro-phenyl)-4-(4-nitrobenzylidene)-5-oxo-4,5-dihydroimidazol-1-yl]-benzene-sulfonamide (10e)

SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C/c2ccc(cc2)[N+]([O-])=O)N=C1c1ccc(Cl)cc1

InChI Key InChIKey=RUEQQEQARLIXFZ-DEDYPNTBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222461   

TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

LigandPNGBDBM222461((E)-4-[2-(4-Chloro-phenyl)-4-(4-nitrobenzylidene)-...)
Affinity DataIC50:  520nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM222461((E)-4-[2-(4-Chloro-phenyl)-4-(4-nitrobenzylidene)-...)
Affinity DataIC50:  4.52E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed