BDBM223563 US9321748, 23
SMILES CC(C)n1cc(nn1)-c1cc(cnc1N)-c1ccc(CN2CCOCC2)c(Cl)c1
InChI Key InChIKey=NTYQUUSEPDYJKL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 223563
Affinity DataIC50: 320nMpH: 8.5 T: 30°CAssay Description:The kinase reaction buffer consists of 50 mM Tris pH 8.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, and 2 mM DTT. In the assay, 1 nM LRRK2 WT or 250 pM ...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,G2019S](Human)
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 220nMpH: 8.5 T: 30°CAssay Description:The kinase reaction buffer consists of 50 mM Tris pH 8.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, and 2 mM DTT. In the assay, 1 nM LRRK2 WT or 250 pM ...More data for this Ligand-Target Pair