BDBM224155 3-{6-(5- chloropyridin-3-yl)- 7-[(trans-4- methylcyclohexyl) methyl]-8-[(2s)-2- (trifluoromethyl) pyrrolidin-1-yl]-7h- purin-2-yl}-1,2,4- oxadiazol-5(4h)-one::US9540377, 16.74
SMILES C[C@H]1CC[C@H](Cn2c(nc3nc(nc(-c4cncc(Cl)c4)c23)-c2noc(=O)[nH]2)N2CCC[C@H]2C(F)(F)F)CC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224155
Affinity DataIC50: 0.585nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair