BDBM22458 2-(cyclooctylamino)-5-ethyl-5-methyl-4,5-dihydro-1,3-thiazol-4-one::2-Amino-1,3-thiazol-4(5H)-one, 5d
SMILES CCC1(C)SC(NC2CCCCCCC2)=NC1=O
InChI Key InChIKey=YRMKTQIBOUAZCQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 22458
Affinity DataKi: 47nM ΔG°: -9.89kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair