BDBM22460 2-Amino-1,3-thiazol-4(5H)-one, 5e::5-ethyl-5-methyl-2-[(2,2,3,3-tetramethylcyclopropyl)amino]-4,5-dihydro-1,3-thiazol-4-one

SMILES CCC1(C)SC(NC2C(C)(C)C2(C)C)=NC1=O

InChI Key InChIKey=WDCSIJCNNMQBAJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22460   

LigandPNGBDBM22460(5-ethyl-5-methyl-2-[(2,2,3,3-tetramethylcyclopropy...)
Affinity DataKi:  58nM ΔG°:  -9.77kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2008
Entry Details Article
PubMed