BDBM224628 US9328111, 1
SMILES CC1(C)CCc2[nH]c3cccc4c3c(n[nH]c4=O)c2C1
InChI Key InChIKey=BDGRZWISYNXFKD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 224628
Affinity DataIC50: 6.30nMpH: 8.0Assay Description:PARP1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP1 was pre-incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 15.6nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair