BDBM22468 2-(adamantan-1-ylamino)-5-ethyl-5-methyl-4,5-dihydro-1,3-thiazol-4-one::2-Amino-1,3-thiazol-4(5H)-one, 5i

SMILES CCC1(C)SC(NC23CC4CC(CC(C4)C2)C3)=NC1=O

InChI Key InChIKey=CSJKLKPBROBUJZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22468   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

LigandPNGBDBM22468(2-(adamantan-1-ylamino)-5-ethyl-5-methyl-4,5-dihyd...)
Affinity DataKi:  24nM ΔG°:  -10.3kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed