BDBM225222 US9328118, 155

SMILES Cn1ccc2c(nc(nc12)C#N)-c1cnc(OCC2CCN(CC(C)(C)O)CC2)c(c1)C(F)(F)F

InChI Key InChIKey=TWQPRXHRKDXOAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225222   

TargetCathepsin S(Human)
Astellas Pharma

US Patent
LigandPNGBDBM225222(US9328118, 155)
Affinity DataIC50: 1.5nMAssay Description:5 μL of a human cathepsin S enzyme (R&D1183-CY-010) was added to a 96-well plate so as to be 20 ng/well. Next, 10-fold dilution of the test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
US Patent