BDBM226611 1-(4-chlorophenyl)-N-((1R,2R,4R,5S)-4- methyl-8-(1H-tetrazol-5-yl)-8- azabicyclo[3.2.1]octan-2-yl)cyclopropane- 1-carboxamide::US20260007684, Compound 80A

SMILES C[C@@H]1C[C@@H](NC(=O)C2(c3ccc(Cl)cc3)CC2)[C@H]2CC[C@@H]1N2c1nnn[nH]1

InChI Key InChIKey=UIIUHHNJWKPSEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226611   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Ventus Therapeutics U.

US Patent
LigandChemical structure of BindingDB Monomer ID 226611BDBM226611(1-(4-chlorophenyl)-N-((1R,2R,4R,5S)-4- methyl-8-(1...)
Affinity DataIC50: 130nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Ventus Therapeutics U.

US Patent
LigandChemical structure of BindingDB Monomer ID 226611BDBM226611(1-(4-chlorophenyl)-N-((1R,2R,4R,5S)-4- methyl-8-(1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent