BDBM227040 US20260008770, Example 63

SMILES CC1CC(c2cccc(-n3cnc4c(C(F)(F)F)c(CN5CCC[C@H](C)C5)[nH]c4c3=O)c2)(c2nncn2C)C1

InChI Key InChIKey=NAIQSKXOPAAIQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227040   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 227040BDBM227040(US20260008770, Example 63)
Affinity DataIC50: 20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent