BDBM227041 US20260008770, Example 64

SMILES Cn1cnnc1CC1(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@H](C6CC6)C5)cc4n3)c2)COC1

InChI Key InChIKey=SMRUPQKOJQQUKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227041   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 227041BDBM227041(US20260008770, Example 64)
Affinity DataIC50: 20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent