BDBM227366 US9328106, 317

SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2ccccc2F)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=FXQXRXUKLGCVRL-NFAWXSAZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227366   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandPNGBDBM227366(US9328106, 317)
Affinity DataKi:  0.00509nM ΔG°:  -15.4kcal/molepH: 7.2 T: 25°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent