BDBM22778 6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione::6,7-dichloro-1,2,3,4-tetrahydroquinoxaline-2,3-dione::Benzil-related compound, 58::CHEMBL284028
SMILES Clc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl
InChI Key InChIKey=AVBSIKMUAFYZAV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 22778
Affinity DataKi: 210nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for its binding affinity towards strychnine - insensitive glycine site of NMDA in presence of [3H]- CPPMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was evaluated for its binding affinity towards strychnine - insensitive glycine site of NMDA receptor in presence of [3H]- GlyMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranesMore data for this Ligand-Target Pair