BDBM228347 US10047093, 8-55

SMILES C[C@]1(O)CC[C@@H](Nc2ccn3ncc(-c4cccc(C(F)(F)F)c4)c3n2)CC1

InChI Key InChIKey=ITUYHNBWFITURV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228347   

TargetSerine/threonine-protein kinase pim-1(Human)
Tolero Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 228347BDBM228347(US10047093, 8-55)
Affinity DataIC50: 54nMT: 2°CAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent