BDBM228720 US10369153, Compound 73::US9346810, 73
SMILES CN([C@@H]1CCN(C1)c1ncnc2[nH]ccc12)c1nc(Cl)cc(C)c1C#N
InChI Key InChIKey=BEULMSQGFTWTJJ-GFCCVEGCSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 228720
Affinity DataIC50: 0.0550nMT: 25°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z'...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMT: 25°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z'...More data for this Ligand-Target Pair