BDBM229594 4-((1R,3s,5S,6r)-6-(1-ethyl- 3-(5-(trifluoromethyl)pyridin- 3-yl)-1H-pyrazol-5-yl)bicyclo [3.1.0]hexan-3-yl)-1,4- oxazepane::US20260008775, Compound 53

SMILES CCn1nc(-c2cncc(C(F)(F)F)c2)cc1[C@H]1[C@@H]2C[C@@H](N3CCCOCC3)C[C@@H]21

InChI Key InChIKey=GBLXRRBNFVMUHM-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229594   

Target7-dehydrocholesterol reductase(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 229594BDBM229594(4-((1R,3s,5S,6r)-6-(1-ethyl- 3-(5-(trifluoromethyl...)
Affinity DataKi:  12.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent