BDBM229673 (R)-4-((1R,3r,5S,6R)-6-(1- isopropyl-3-(2-(trifluoro- methyl)pyrimidin-5-yl)-1H- pyrazol-5-yl)bicyclo[3.1.0] hexan-3-yl)-3-methylmor- pholine::US20260008775, Compound 97

SMILES CC(C)n1nc(-c2cnc(C(F)(F)F)nc2)cc1[C@H]1[C@@H]2C[C@H](N3CCOC[C@H]3C)C[C@@H]21

InChI Key InChIKey=UMDBQCCPYNMFJG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229673   

Target7-dehydrocholesterol reductase(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 229673BDBM229673((R)-4-((1R,3r,5S,6R)-6-(1- isopropyl-3-(2-(trifluo...)
Affinity DataKi:  15.1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent