BDBM229745 4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(2-(trifluorometh- yl)pyridin-4-yl)-1H-pyrazol- 5-yl)bicyclo[3.1.0]hexan-3- yl)morpholine::US20260008775, Compound 172

SMILES CC(C)n1nc(-c2ccnc(C(F)(F)F)c2)cc1[C@H]1[C@@H]2C[C@H](N3CCOCC3)C[C@@H]21

InChI Key InChIKey=NCKKMRNALMGTPF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229745   

Target7-dehydrocholesterol reductase(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 229745BDBM229745(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(2-(trifluorom...)
Affinity DataKi:  13.4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent