BDBM229750 4-((1R,3s,5S,6r)-6-(3-(5- chloropyridin-3-yl)-1-iso- propyl-1H-pyrazol-5-yl)- bicyclo[3.1.0]hexan-3-yl)- 1,4-oxazepane::US20260008775, Compound 177*

SMILES CC(C)n1nc(-c2cncc(Cl)c2)cc1[C@H]1[C@@H]2C[C@@H](N3CCCOCC3)C[C@@H]21

InChI Key InChIKey=OPCAPQWNSHQEAQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229750   

Target7-dehydrocholesterol reductase(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 229750BDBM229750(4-((1R,3s,5S,6r)-6-(3-(5- chloropyridin-3-yl)-1-is...)
Affinity DataKi:  15.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent