BDBM230656 US9340517, 105
SMILES NC(=N)NCCC[C@H]1N[C@@H](CNC(=O)c2ccc3ccccc3c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O
InChI Key InChIKey=DKFQXTHTGAKMJQ-XLJNKUFUSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 230656
Affinity DataIC50: <100nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.28E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 6.03E+3nMAssay Description:Radioligand binding and cAMP assays were also conducted using membranes and cells expressing MC5R cloned from other species (mouse MC5R membranes wer...More data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Radioligand binding and cAMP assays were also conducted using membranes and cells expressing MC5R cloned from other species (mouse MC5R membranes wer...More data for this Ligand-Target Pair