BDBM231008 US9340549, 26::US9340549, 27
SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)NC(=O)c1cccc2cccnc12
InChI Key InChIKey=REUQDXNRIHMJKE-HFMPRLQTSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 231008
Affinity DataIC50: 10.3nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 20.1nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 4.78nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair