BDBM232204 3,4,5-Trimethoxycinnamic acid (TMCA)

SMILES COc1cc(\C=C\C(O)=O)cc(OC)c1OC

InChI Key InChIKey=YTFVRYKNXDADBI-SNAWJCMRSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 232204   

Target5-hydroxytryptamine receptor 1A(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50:  7.60E+3nMpH: 7.4 T: 27°CAssay Description:For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50:  2.50E+3nMpH: 7.4Assay Description:Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 27°CAssay Description:For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 27°CAssay Description:For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Ewha Womans University

LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50:  7.60E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed