BDBM233710 US9353066, 3.8

SMILES Cc1cc(Nc2nccc(n2)C(F)(F)F)cc(c1)-c1ccc(OCc2ccccc2)c(c1)C(O)=O

InChI Key InChIKey=OXZJSSPBUVENME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233710   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233710(US9353066, 3.8)
Affinity DataIC50:  11.5nMpH: 7.5 T: 25°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent